In the study of aging and metabolic health, mitochondria—the powerhouses of the cell—are a primary focus. As organisms age, mitochondrial efficiency declines, leading to increased oxidative stress. Two research peptides are at the forefront of mitochondrial studies: MOTS-c and SS-31.

## MOTS-c: The Metabolic Regulator

MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial genome itself. In laboratory research, MOTS-c is studied for its ability to act as an exercise mimetic. It regulates glucose homeostasis and promotes the uptake of glucose into cells, making it a highly valuable compound for metabolic and obesity research.

## SS-31 (Elamipretide): The Inner Membrane Protector

While MOTS-c regulates metabolism, SS-31 targets the structural integrity of the mitochondria. SS-31 is a cell-penetrating tetrapeptide that selectively targets the inner mitochondrial membrane. It binds to cardiolipin, a lipid essential for the electron transport chain. By stabilizing cardiolipin, SS-31 is researched for its ability to prevent oxidative damage and restore cellular energy production.

Explore our premium mitochondrial research peptides at Pure Peptides UK.

*Disclaimer: All products are strictly for in vitro laboratory research. Not for human use.*